R&D Services

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  • Custom and challenging Science solutions

  • State of the Art Facilities, Instrumentation and Software

  • 70% PhD

AREAS OF SPECIALTY / EXPERTISE

Chemistry

  • Small (mg) to medium (100 g) scale, libraries, complex small molecule synthesis

  • Peptide, cannabinoids, controlled substances, preparative HPLC

 

Cell biology

  • Custom assays, Luminex, RT-PCR, Immuno-assays, CRISPR, protein degradation, proliferation, Internal bank of cancer/normal cell lines, primary cell models, stable/transient cell line generation, FACS

 

Analytical

  • LC-MS/MS, NMR(1H,13C,19F), LCMS, HPLC; +  

 

Biochemistry, Biophysics 

  • Custom assays, Fluorometric and colorimetric, radiometric assays, FPLC

  • Binding assays: SPR, ITC, thermal, isothermal denaturation, protein expression, mutagenesis. 

 

ADME, Bioanalytical

  • GSH/GST, whole blood, plasma and microsomal stability, Caco-2, solubility, PPB, LogD

 

Proteomics, Bioinformatics

  • SILAC, pulse-chase; targeted and shotgun MS-based proteomics and downstream bioinformatic analyses; covalent, PTM analysis

  • Target ID from proteomic data, Development and implementation of biomarker qualification/validation strategy

FACILITIES, SOFTWARE & EQUIPMENT

12,500 sqft​ of state-of-the-art laboratories and equipment​ with expansion plans underway​.

Licensed for cannabinoid & controlled substances.

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Liquid Scintillation Counter

Liquid Scintillation Counter

MagPix

MagPix

Microcal PEAQ-ITC

Microcal
PEAQ-ITC

CytoFlexS FACs

CytoFlexS FACs

Microplate Readers and Fluorescence Microscopes

Microplate Readers
and Fluorescence Microscopes

Biotage Isolera Flash Chromatography

Biotage Isolera Flash Chromatography

Biotage Peptide Synthesizer
Analytical and preparative HPLC units
400 MHz NMR

Biotage Peptide Synthesizer

Analytical and preparative
HPLC units

400 - 600 MHz NMR

Biotage Microwave Initiator

Biotage
Microwave Initiator

Biacore T200 SPR

Biacore T200 SPR

Variety of LC/MS and LC/MS/MS

Variety of LC/MS and LC/MS/MS

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Jess Instrument

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Lyophilizer