Custom and challenging Science solutions
State of the Art Facilities, Instrumentation and Software
AREAS OF SPECIALTY / EXPERTISE
Small (mg) to medium (100 g) scale, libraries, complex small molecule synthesis
Peptide, cannabinoids, controlled substances, preparative HPLC
Custom assays, Luminex, RT-PCR, Immuno-assays, CRISPR, protein degradation, proliferation, Internal bank of cancer/normal cell lines, primary cell models, stable/transient cell line generation, FACS
LC-MS/MS, NMR(1H,13C,19F), LCMS, HPLC; +
Custom assays, Fluorometric and colorimetric, radiometric assays, FPLC
Binding assays: SPR, ITC, thermal, isothermal denaturation, protein expression, mutagenesis.
GSH/GST, whole blood, plasma and microsomal stability, Caco-2, solubility, PPB, LogD
SILAC, pulse-chase; targeted and shotgun MS-based proteomics and downstream bioinformatic analyses; covalent, PTM analysis
Target ID from proteomic data, Development and implementation of biomarker qualification/validation strategy
FACILITIES, SOFTWARE & EQUIPMENT
12,500 sqft of state-of-the-art laboratories and equipment with expansion plans underway.
Licensed for cannabinoid & controlled substances.
Liquid Scintillation Counter
and Fluorescence Microscopes
Biotage Isolera Flash Chromatography
Biotage Peptide Synthesizer
Analytical and preparative
400 - 600 MHz NMR
Biacore T200 SPR
Variety of LC/MS and LC/MS/MS